November 25, 2009

Anne Soikkeli, Cristina Sempio, Ann Marie Kaukonen, Arto Urtti, Jouni Hirvonen, and Marjo Yliperttula

Feasibility Evaluation of 3 Automated Cellular Drug Screening Assays on a Robotic Workstation
J Biomol Screen first published on November 25, 2009 as doi:10.1177/1087057109352236
[Abstract] [OnlineFirst PDF]  

Swapan Chakrabarti, Stan R. Svojanovsky, Romana Slavik, Gunda L. Georg, George S. Wilson, and Peter G. Smith

Artificial Neural Network-Based Analysis of High-Throughput Screening Data for Improved Prediction of Active Compounds
J Biomol Screen first published on November 25, 2009 as doi:10.1177/1087057109351312
[Abstract] [OnlineFirst PDF]  

Anne Kümmel, Hanspeter Gubler, Patricia Gehin, Martin Beibel, Daniela Gabriel, and Christian N. Parker

Integration of Multiple Readouts into the Z' Factor for Assay Quality Assessment
J Biomol Screen first published on November 25, 2009 as doi:10.1177/1087057109351311
[Abstract] [OnlineFirst PDF]  

November 12, 2009

Janet Newman, Vincent J. Fazio, Tom T. Caradoc-Davies, Kim Branson, and Thomas S. Peat

Practical Aspects of the SAMPL Challenge: Providing an Extensive Experimental Data Set for the Modeling Community
J Biomol Screen first published on November 12, 2009 as doi:10.1177/1087057109348220
[Abstract] [Free OnlineFirst PDF]  
SAGE Open article 

November 9, 2009

Johanna S. Blees, Tobias Schmid, Cheryl L. Thomas, Alyson R. Baker, Lauren Benson, Jason R. Evans, Ekaterina I. Goncharova, Nancy H. Colburn, James B. McMahon, and Curtis J. Henrich

Development of a High-Throughput Cell-Based Reporter Assay to Identify Stabilizers of Tumor Suppressor Pdcd4
J Biomol Screen first published on November 9, 2009 as doi:10.1177/1087057109351028
[Abstract] [OnlineFirst PDF]  

November 3, 2009

Romel Somwar, David Shum, Hakim Djaballah, and Harold Varmus

Identification and Preliminary Characterization of Novel Small Molecules That Inhibit Growth of Human Lung Adenocarcinoma Cells
J Biomol Screen first published on November 3, 2009 as doi:10.1177/1087057109350919
[Abstract] [OnlineFirst PDF]  

November 2, 2009

Pauline T. Lieu, Thomas Machleidt, Bhaskar Thyagarajan, Andrew Fontes, Elizabeth Frey, Maya Fuerstenau-Sharp, David V. Thompson, Geetha M. Swamilingiah, Suchitra S. Derebail, David Piper, and Jonathan D. Chesnut

Generation of Site-Specific Retargeting Platform Cell Lines for Drug Discovery Using phiC31 and R4 Integrases
J Biomol Screen first published on November 2, 2009 as doi:10.1177/1087057109348941
[Abstract] [Free OnlineFirst PDF]  
SAGE Open article 

October 19, 2009

Karla Kopec, Bruce Jones, Jeffrey C. Thomas, Chrysanthe Spais, Beth Ann McKenna, Lisa Saville, Jean Husten, Sheryl Meyer, Mark Ator, and Emir Duzic

Successful Identification of Glycine Transporter Inhibitors Using an Adaptation of a Functional Cell-Based Assay
J Biomol Screen first published on October 19, 2009 as doi:10.1177/1087057109347779
[Abstract] [OnlineFirst PDF]  

October 14, 2009

Fred Parham, Chris Austin, Noel Southall, Ruili Huang, Raymond Tice, and Christopher Portier

Dose-Response Modeling of High-Throughput Screening Data
J Biomol Screen first published on October 14, 2009 as doi:10.1177/1087057109349355
[Abstract] [OnlineFirst PDF]  

October 12, 2009

Zhengrong Zhu and John Cuozzo

High-Throughput Affinity-Based Technologies for Small-Molecule Drug Discovery
J Biomol Screen first published on October 12, 2009 as doi:10.1177/1087057109350114
[Abstract] [OnlineFirst PDF]  

Zangwei Xu, Kumiko Nagashima, Dongyu Sun, Thomas S. Rush, Alan Northrup, Jannik N. Andersen, Ilona Kariv, and Ekaterina V. Bobkova

Development of High-Throughput TR-FRET and AlphaScreen Assays for Identification of Potent Inhibitors of PDK1
J Biomol Screen first published on October 12, 2009 as doi:10.1177/1087057109349356
[Abstract] [OnlineFirst PDF]  

Thomas Zielinski, Adam J. Kimple, Stephanie Q. Hutsell, Mark D. Koeff, David P. Siderovski, and Robert G. Lowery

Two G_i1 Rate-Modifying Mutations Act in Concert to Allow Receptor-Independent, Steady-State Measurements of RGS Protein Activity
J Biomol Screen first published on October 12, 2009 as doi:10.1177/1087057109347473
[Abstract] [OnlineFirst PDF]  

Qingyan Au, Yingjia Zhang, Jack R. Barber, Shi Chung Ng, and Bin Zhang

Identification of Inhibitors of HSF1 Functional Activity by High-Content Target-Based Screening
J Biomol Screen first published on October 12, 2009 as doi:10.1177/1087057109347472
[Abstract] [OnlineFirst PDF]  

October 2, 2009

Nesar Akanda, Peter Molnar, Maria Stancescu, and James J. Hickman

Analysis of Toxin-Induced Changes in Action Potential Shape for Drug Development
J Biomol Screen first published on October 2, 2009 as doi:10.1177/1087057109348378
[Abstract] [OnlineFirst PDF]  

September 22, 2009

Xue Li, Jun Yang, Xiaobo He, Zhaoyong Yang, Yan Ding, Pei Zhao, Zongying Liu, Huayi Shao, Zhuorong Li, Yueqin Yang, and Shuyi Si

Identification of Upregulators of BMP2 Expression via High-Throughput Screening of a Synthetic and Natural Compound Library
J Biomol Screen first published on September 22, 2009 as doi:10.1177/1087057109346446
[Abstract] [OnlineFirst PDF]  

Nunzianna Doti, Daniela Marasco, Carlo Pedone, Marco Sabatella, and Menotti Ruvo

Optimizing a Kinase Assay for IKKB on an HTS Station
J Biomol Screen first published on September 22, 2009 as doi:10.1177/1087057109345527
[Abstract] [OnlineFirst PDF]  

February 12, 2008

Christian Parker

Book Review: Antisense Drug Technology, Principles, Strategies and Applications, 2nd Ed
J Biomol Screen first published on February 12, 2008 as doi:10.1177/1087057108314578
[OnlineFirst PDF]