Journal of Biomolecular Screening

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Click here for more information

Sign In to gain access to subscriptions and/or personal tools.
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (12)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Beske, O.
Right arrow Articles by Goldbard, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Beske, O.
Right arrow Articles by Goldbard, S.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
Journal of Biomolecular Screening, Vol. 9, No. 3, 173-185 (2004)
DOI: 10.1177/1087057103260088
© 2004 Society for Biomolecular Sciences

A Novel Encoded Particle Technology that Enables Simultaneous Interrogation of Multiple Cell Types

Oren Beske

Vitra Bioscience, Inc., Mountain View, CA.

Jinjiao Guo

Vitra Bioscience, Inc., Mountain View, CA.

Jianren Li

Vitra Bioscience, Inc., Mountain View, CA.

Daniel Bassoni

Vitra Bioscience, Inc., Mountain View, CA.

Kimberly Bland

Vitra Bioscience, Inc., Mountain View, CA.

Holly Marciniak

Vitra Bioscience, Inc., Mountain View, CA.

Mike Zarowitz

Vitra Bioscience, Inc., Mountain View, CA.

Vladimir Temov

Vitra Bioscience, Inc., Mountain View, CA.

Ilya Ravkin

Vitra Bioscience, Inc., Mountain View, CA.

Simon Goldbard

Vitra Bioscience, Inc., Mountain View, CA.

The authors have developed a cellular analysis platform, based on encoded microcarriers, that enables the multiplexed analysis of a diverse range of cellular assays. At the core of this technology are classes of microcarriers that have unique, identifiable codes that are deciphered using CCD-based imaging and subsequent image analysis. The platform is compatible with a wide variety of cellular imaging-based assays, including calcium flux, reporter gene activation, cytotoxicity, and proliferation. In addition, the platform is compatible with both colorimetric and fluorescent readouts. Notably, this technology has the unique ability to multiplex different cell lines in a single microplate well, enabling scientists to perform assays and data analysis in novel ways.

Key Words: multiplexing • imaging • cell-based assays • particle technology • cells • microarrays


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 J Biomol ScreenHome page
J. J. Miret, J. Zhang, H. Min, K. Lewis, M. Roth, M. Charlton, and P. H. Bauer
Multiplexed G-Protein-Coupled Receptor Ca2+ Flux Assays for High-Throughput Screening
J Biomol Screen, December 1, 2005; 10(8): 780 - 787.
[Abstract] [PDF]