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Journal of Biomolecular Screening
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A Simple Automated Solution for Removing and Applying Sealing Microplate Lids

Glenn A. Clarke

Department of Research Operations, Merck Research Laboratories, Rahway, NJ

Marc N. Feiglin

Department of Research Information Systems-Laboratory Automation, Merck Research Laboratories, Rahway, NJ

Greg W. King

Department of Research Operations, Merck Research Laboratories, Rahway, NJ

Jamie Bishop

Department of Research Operations, Merck Research Laboratories, Rahway, NJ

Stephen Skwish

Department of HTS and Automation, Merck Research Laboratories, Rahway, NJ

Gary S. Kath

Department of Research Operations, Merck Research Laboratories, Rahway, NJ

With the improved reliability and efficiency of automation, there has been an increased desire to integrate automated sample management with automated screening systems. In order to store samples "on line" for an extended period of time, an automation-compatible means for sealing and unsealing microplates is necessary. Numerous commercial solutions are available for removing loose-fitting microplate lids; however, the task of removing a tight-fitting matted lid such as the RoboLid is more challenging. This paper discusses the design of an automated workstation for the application and removal of such tight-fitting microplate lids.

Journal of Biomolecular Screening, Vol. 6, No. 5, 333-338 (2001)
DOI: 10.1177/108705710100600507
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Home page
 J Biomol ScreenHome page
W. P. Janzen and I. G. Popa-Burke
Review: Advances in Improving the Quality and Flexibility of Compound Management
J Biomol Screen, June 1, 2009; 14(5): 444 - 451.
[Abstract] [PDF]