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Journal of Biomolecular Screening
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High Throughput Screening for Drug Discovery: Continually Transitioning into New Technology

Sandra Fox

HighTech Business Decisions, Moraga, CA

Shauna Farr-Jones

HighTech Business Decisions, Moraga, CA

Mary Alice Yund

HighTech Business Decisions, Moraga, CA

Those working in HTS laboratories, pressured to find increasing numbers of drug leads while containing costs, are seeking larger compound sets, more automated systems to screen them faster, and an integrated set of equipment and consumables. Enabling technologies are continually being developed and suppliers are teaming up to supply integrated equipment and consumable sets. Miniaturization, microfluidic chips, subnanoliter dispensing, fluorescence, homogeneous assays for HTS, and virtual screening are just some of the evolving tools that HTS experts are continually evaluating and incorporating into drug discovery operations.

Journal of Biomolecular Screening, Vol. 4, No. 4, 183-186 (1999)
DOI: 10.1177/108705719900400405
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 J Biomol ScreenHome page
P. Banks, M. Gosselin, and L. Prystay
Impact of a Red-Shifted Dye Label for High Throughput Fluorescence Polarization Assays of G Protein-Coupled Receptors
J Biomol Screen, October 1, 2000; 5(5): 329 - 334.
[Abstract] [PDF]